Movie

The Substance

“Have you ever dreamt of a better version of yourself?”

★ 7.1(6,043)20242h 21m

The Substance is streaming on HBO Max, MUBI, HBO Max Amazon Channel and MUBI Amazon Channel in Mexico, and available to rent or buy on Apple TV Store and Amazon Video. Availability checked 12 June 2026.

Where to watch The Substance

🇲🇽 Mexico

HBO MaxStream

MUBIStream

HBO Max Amazon ChannelStream

MUBI Amazon ChannelStream

Good to know

Director: Coralie Fargeat
Release date: 2024-09-07
Runtime: 2h 21m
Language: English
Box office: $77,316,812
Budget: $17,500,000
Status: Released
Country: France
Studio: Working Title Films

The Substance — trailer

About The Substance

The Substance is a 2024 movie in the Horror, Science Fiction and Thriller genres, directed by Coralie Fargeat, starring Demi Moore, Margaret Qualley and Dennis Quaid. It has a runtime of 2 hours 21 minutes. It holds an average rating of 7.1/10 from 6,043 viewers. Below you can see where to watch The Substance in Mexico — across streaming, rental and purchase options — along with the full cast, trailer and viewer reviews.

Synopsis

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Cast

Demi Moore

Elisabeth

Margaret Qualley

Sue

Dennis Quaid

Harvey

Edward Hamilton-Clark

Fred

Gore Abrams

Oliver

Oscar Lesage

Troy

Christian Erickson

Man at Diner

Robin Greer

Male Nurse

Tom Morton

Doctor

Hugo Diego Garcia

Diego - Boyfriend

Daniel Knight

Casting Director

Jonathon Carley

Assistant Casting Director

Themes & keywords

new year's evecapitalismbirthdayblack marketidentitydark comedybeautysatireagingcelebrityfemale protagonistlos angeles, californiahas beenaerobicsdisfigurement

Frequently asked questions

Where can I watch The Substance in Mexico?+

In Mexico, you can stream The Substance on HBO Max, MUBI, HBO Max Amazon Channel and MUBI Amazon Channel. It's also available to rent or buy on Apple TV Store and Amazon Video.

Is The Substance on Netflix?+

The Substance is not on Netflix in Mexico right now, but you can stream it on HBO Max, MUBI, HBO Max Amazon Channel and MUBI Amazon Channel.

How long is The Substance?+

The Substance has a runtime of 2 hours 21 minutes (141 minutes).

Who stars in The Substance?+

The Substance stars Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark and Gore Abrams.

When did The Substance come out?+

The Substance is a 2024 movie directed by Coralie Fargeat.

What genre is The Substance?+

The Substance is Horror, Science Fiction and Thriller film.

Who directed The Substance?+

The Substance was directed by Coralie Fargeat.